What’s TS-ONE ®

TS-ONE ® is a fluoropyrimidine anticancer drug. It is developed to reduce the adverse drug reactions while enhancing the effectiveness of 5-fluorouracil (5-FU)1.

TS-ONE ® is a combination of three pharmacological compounds below.

Tegafur becomes 5-FU when metabolized.
5-FU can prevent the growth of cancer cells or result in cancer cell death.

Gimeracil inhibits 5-FU degradation, and sustains anti-tumor activity.

Oteracil Potassium reduces digestive side effects such as diarrhea, while reducing toxicity associate with 5-FU.
In Hong Kong, TS-ONE ® is indicated for post operative adjuvant chemotherapy for locally advanced (stage II (excluding T1), IIIA or IIIB) gastric cancer2.

TS-ONE ® Capsule 20

TS-ONE 20mg Capsule

TS-ONE ® Capsule 25

TS-ONE 25mg Capsule

Important Considerations

TS-ONE ® is an oral drug approved in most Asian regions and European countries under different brand names3. TS-ONE ® is a convenient oral dosage form that does not require it to be administered in the hospital, for example, it can be taken at home or at work.
Frequent monitoring may be required. It is important to adhere to the information provided by your doctor to ensure safe and effective use of TS-ONE ® .

TS-ONE Capsule

Brand Names

TS-1 / TS-1 / TS-ONE / TS-ONE / TS-ONE / TS-ONE / TS-ONE / TS-ONE / TS-ONE / TS-ONE / Teysuno / Teysuno / 愛斯萬 / 愛斯万


  1. Shirasaka T et al. Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators.
    Anticancer Drugs., 1996;7:548-557.
  2. TS-ONE PI HK. DKSH Hong Kong Limited.
  3. TS-ONE Worldwide Marketing Approval Status, June 2020.